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    Nanoemulsions & Liposomes

    Manufacture pharmaceutical,
    food and cosmetic nanoemulsions,
    nanocrystals and liposomes.

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    Medical Cannabis Formulations

    Produce water‑soluble CBD and 
    THC nanoemulsions with enhanced 
    bioavailability and rapid action.

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    Degassing of
    liquids

    Remove dissolved gases and micro‑bubbles from oils, waxes, detergents and adhesives.

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    Cell Distruption & Extraction

    Extract oils and recover bioactive compounds by lysing plant and microbial cells.

  • Nanoemulsions & Liposomes

    Nanoemulsions & Liposomes

    Manufacture pharmaceutical, food and cosmetic nanoemulsions, nanocrystals and liposomes.

  • Medical Cannabis Formulations

    Medical Cannabis Formulations

    Produce water-soluble CBD and THC nanoemulsions with enhanced bioavailability and rapid action.

  • Degassing of liquids

    Degassing of
    liquids

    Remove dissolved gases and micro‑bubbles from oils, waxes, detergents and adhesives.

  • Cell Disruption and Extraction

    Cell Disruption & Extraction

    Extract oils and recover bioactive compounds
    by lysing plant and microbial cells.

ISM is a research & development, equipment design and process consulting firm, specializing in scalable high-intensity ultrasonic technology.

Ultrasonic Processors

LSP-600
Laboratory-Scale Processor
BSP-1200
Bench-Scale Processor
ISP-3600
Industrial-Scale Processor

Have Questions?

Consult with an application specialist
or request a quotation.

Contact Us
  • Blog
  • Blog
  • Case Studies
  • Testimonials
  • Intellectual Property
  • What is BHUT?
Alexey Peshkovsky, Industrial Sonomechanics - Speaking at NECANN Boston
03/03/23

ISM Will Be Presenting at the 2023 NECANN in Boston, MA

We are excited to announce that Industrial Sonomechanics (ISM) will ... Read more...
Sonomechanics at Pittcon 2023
01/24/23

ISM is Exhibiting at 2023 Pittcon in Philadelphia, PA

This March, Industrial Sonomechanics (ISM) will participate in the 2... Read more...
Alexey Peshkovsky speaking at Wonderland Miami 2022
11/01/22

ISM Will Be Participating in 2022 Wonderland Event in Miami, FL

We are excited to announce that Industrial Sonomechanics (ISM) will ... Read more...
Read all blog posts
All-Natural CBD Extract Nanoemulsion
CASE STUDY

Download PDF

Ultrasonic Nanocrystallization
CASE STUDY

Download PDF

Ultrasonic Disruption of Yeast Cells
CASE STUDY

Download PDF

Scaling Up the Production of a Nanoemulsion
CASE STUDY

Download PDF

Read more case studies

Khara Cartagena, Cannabis and Hemp Productions

“We recently purchased a BSP-1200 system from ISM and were very impressed with its performance. The word got out, and one of our customers came to our facility to perform CBD-oil emulsion tests with the system. Though he was initially skeptical, after running the machine for only 1 min he got far better results to what he was able to achieve in over an hour with his conventional ultrasonic processor. He absolutely loved the BSP-1200 and bought it off from us that same day to take to his facility in CA! We have now decided to go straight for ISM’s production-scale ISP-3000 processor.”

See all testimonials

See all testimonials

EFFICIENT COOLING OF PIEZOELECTRIC TRANSDUCERS

United States Patent # 9,142,751, September 22, 2015

Alexey S. Peshkovsky, Sergei L. Peshkovsky

Abstract: A sealed piezoelectric transducer having a single, uniform, electrically insulating, heat-conducting layer of a soft, rubbery material filled with a fine, homogeneously-dispersed powder having high thermal conductivity. The material is placed in contact with the surfaces of the transducer and conducts the heat from the surfaces to an external heat sink. Since the thermally conductive powder is fully encapsulated in the rubbery material, its abrasive properties are neutralized.

See all intellectual property

Download PDF

See all patents

High ultrasonic amplitudes able to generate intense acoustic cavitation are required for most processes.

Unlike conventional ultrasonic devices, our patented Barbell Horn Ultrasonic Technology (BHUT)-based processors make it possible to produce extremely high ultrasonic amplitudes at any scale, from laboratory to industrial, guaranteeing reproducible results after scale-up.

Learn More

 
Ultrasonic Production of Water-Soluble Cannabis, Kratom, & Other Bioactives, 2022 Delta 8 & CBD Expo
Large-Capacity In-Line Filter: Assembly, Nanoemulsion Filtration, Cleaning, & Storage Procedures
Industrial Sonomechanics® at MJBizCon 2021 in Las Vegas, NV
“Water-Soluble” Cannabis: Ultrasonic Production of Liquid & Powdered Nanoemulsions
Barbell Horn Ultrasonic Technology (BHUT) Introduction and How We Scale Up
Interview with Dr. Alexey Peshkovsky at 2021 CBDExpo
Overview of Nano-Emulsification Process with BSP-1200 Ultrasonic Processor
Water-Soluble Cannabis Extract Nanoemulsions, by Dr. Alexey Peshkovsky, Industrial Sonomechanics
Dr. Alexey Peshkovsky speaking at the University of Cauca, Colombia
Podcast: Make & Measure the Potency of Cannabis Extract Nanoemulsions
Plant 2 Product: Production of Cannabis Beverages & Water-Soluble Powders
Barbell Horn Replacement Procedure for ISM Ultrasonic Processors
Do I Need Technical Background to Make Nanoemulsions with ISM Technology
 
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