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    Nanoemulsions & Liposomes

    Manufacture pharmaceutical,
    food and cosmetic nanoemulsions,
    nanocrystals and liposomes.

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    Medical Cannabis Formulations

    Produce water‑soluble CBD and 
    THC nanoemulsions with enhanced 
    bioavailability and rapid action.

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    Degassing of
    liquids

    Remove dissolved gases and micro‑bubbles from oils, waxes, detergents and adhesives.

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    Cell Distruption & Extraction

    Extract oils and recover bioactive compounds by lysing plant and microbial cells.

  • Nanoemulsions & Liposomes

    Nanoemulsions & Liposomes

    Manufacture pharmaceutical, food and cosmetic nanoemulsions, nanocrystals and liposomes.

  • Medical Cannabis Formulations

    Medical Cannabis Formulations

    Produce water-soluble CBD and THC nanoemulsions with enhanced bioavailability and rapid action.

  • Degassing of liquids

    Degassing of
    liquids

    Remove dissolved gases and micro‑bubbles from oils, waxes, detergents and adhesives.

  • Cell Disruption and Extraction

    Cell Disruption & Extraction

    Extract oils and recover bioactive compounds
    by lysing plant and microbial cells.

Ultrasonic Processors

LSP-600
Laboratory-Scale Processor
BSP-1200
Bench-Scale Processor
ISP-3000
Industrial-Scale Processor

make your own nanoformulations

on any scale

ISM is a research & development, equipment design and process consulting firm, specializing in scalable high-intensity ultrasonic technology. We focus on providing the tools to make nanoemulsions, nanocrystals, and liposomes to the pharmaceutical, cosmetic, medical cannabis, and food & beverage industries. Other target applications include cell disruption, aqueous and solvent-based oil extraction, liquid degassing, nanoparticle deagglomeration, and sonochemistry. Our mission is to enable our clients to optimize these ultrasonic processes and implement them in commercial production.

Have Questions?

Consult with an application specialist
or request a quotation.

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ISM System are Proudly Made in the USA
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  • What is BHUT?

Webinar Video and Q&As: Analysis, Optimization & Production of Translucent Nanoemulsions
11/10/20

Webinar Video and Q&As: Analysis, Optimization & Production of Translucent Nanoemulsions

The video recording of our recent webinar, "Analysis, Optimizatio... Read more...
ISM Research Paper: Cannabis extract nanoemulsions produced by high-intensity ultrasound: Formulation development and scale-up
09/23/20

Cannabis Research Publication in the Journal of Drug Delivery Science & Technology

Industrial Sonomechanics® (ISM) is pleased to announce that ou... Read more...
Live webinar: Analysis, Optimization and Production of Translucent Nanoemulsions
08/24/20

Live Webinar: Analysis, Optimization & Production of Translucent Nanoemulsions

Industrial Sonomechanics (ISM) is pleased to invite you to a l... Read more...

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All-Natural CBD Extract Nanoemulsion
CASE STUDY

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Ultrasonic Nanocrystallization
CASE STUDY

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Ultrasonic Disruption of Yeast Cells
CASE STUDY

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Scaling Up the Production of a Nanoemulsion
CASE STUDY

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Khara Cartagena, Cannabis and Hemp ProductionsMay 2016

"We recently purchased a BSP-1200 system from ISM and were very impressed with its performance. The word got out, and one of our customers came to our facility to perform CBD-oil emulsion tests with the system. Though he was initially skeptical, after running the machine for only 1 min he got far better results to what he was able to achieve in over an hour with his conventional ultrasonic processor. He absolutely loved the BSP-1200 and bought it off from us that same day to take to his facility in CA! We have now decided to go straight for ISM's production-scale ISP-3000 processor."

See all testimonials

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EFFICIENT COOLING OF PIEZOELECTRIC TRANSDUCERS

United States Patent # 9,142,751, September 22, 2015

Alexey S. Peshkovsky, Sergei L. Peshkovsky

Abstract: A sealed piezoelectric transducer having a single, uniform, electrically insulating, heat-conducting layer of a soft, rubbery material filled with a fine, homogeneously-dispersed powder having high thermal conductivity. The material is placed in contact with the surfaces of the transducer and conducts the heat from the surfaces to an external heat sink. Since the thermally conductive powder is fully encapsulated in the rubbery material, its abrasive properties are neutralized.

See all intellectual property

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See all patents

High ultrasonic amplitudes able to generate intense acoustic cavitation are required for most processes.

Unlike conventional ultrasonic devices, our patented Barbell Horn Ultrasonic Technology (BHUT)-based processors make it possible to produce extremely high ultrasonic amplitudes at any scale, from laboratory to industrial, guaranteeing reproducible results after scale-up.

Learn More

Industrial Sonomechanics® at the 2020 White Label Expo, Highlights
Water-Soluble Cannabis Extract Nanoemulsions, by Dr. Alexey Peshkovsky, Industrial Sonomechanics
Why and How to Make Cannabis Extracts “Water-Soluble” – a Presentation by Dr. Alexey Peshkovsky
Barbell Horn Ultrasonic Technology Introduction and How We Scale Up
Dr. Alexey Peshkovsky speaking at the University of Cauca, Colombia
Ultrasonics 2016 Conference Presentation by Dr. Alexey Peshkovsky, President & Chief Scientific Officer of ISM
Translucent Nanoemulsion Produced with ISM Industrial-Scale Ultrasonic Liquid Processor, ISP-3000
BSP-1200 Bench-Scale Ultrasonic Processor: Barbell Horn Replacement Procedure
Webcast Recording: Ultrasonic Liquid Processing for Cannabis Oil Nano-Emulsification and Extraction
Watch All videos

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Miami, FL 33155
Address: 7440 SW 50th Terrace #110 Miami, FL 33155
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