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WATER-SOLUBLE CANNABIS FORMULATIONS

Produce your own water-soluble THC and CBD nanoemulsions. No technical background necessary.

  • Create fast-acting and highly bioavailable liquid and powdered cannabis nano-formulations.
  • Follow our detailed SOPs for optimal results.
Schedule A Call

NANOEMULSIONS, LIPOSOMES
& MORE

Manufacture pharmaceutical, nutraceutical, food & beverage, and cosmetic nano-formulations.

  • Create fast-acting and highly bioavailable liquid and powdered nano-formulations.
  • Use our custom formulation development services.
Schedule A Call

IN-LINE DEGASSING & DEHYDRATION

Remove dissolved/entrained gases and water from fuels, oils, waxes, detergents, and adhesives.

  • Improve performance by preventing oxidation, increased
    conductivity, and other unwanted processes.
  • Improve visual appearance and filling operations.
Schedule A Call

EXTRACTION BY CELL DISRUPTION

Extract a wide range of active ingredients from mushrooms, plants and microorganisms.

  • Increase extraction rates and product yields, simplify post-processing procedures.
  • Replace harsh organic solvents with green alternatives.
Schedule A Call
Ultrasonic nanoemulsion production banner – Industrial Sonomechanics continuous degassing machine

ISM is a research & development, equipment design and process consulting firm, specializing in scalable high-intensity ultrasonic technology.

Ultrasonic Processors

LSP-600
Laboratory-Scale Processor
BSP-1200
Bench-Scale Processor
ISP-3600
Industrial-Scale Processor
High Ultrasonic Amplitudes

High Ultrasonic Amplitudes

Generate unprecedented cavitation & shear force intensities at any scale, from lab to industrial.

Seamless Scale-Up

Seamless Scale-Up to Production

Transfer from the lab to production while maintaining the highest finished product quality.

24/7 Production-Scale Processing

24/7 Production-Scale Processing

Continuously operate the equipment for as long as required, without interruptions.

Wide-Range Temperature Control

Precise Temperature Control

Maintain the temperature of your liquid material at any desired
level in a wide range.

Have Questions?

Consult with an application specialist
or request a quotation.

Contact Us
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Recap: Adhesives & Bonding Expo
08/03/26

Recap: Adhesives & Bonding Expo

Recap: Adhesives & Bonding Expo

Industrial Sonomechanics (ISM) had a great time exhibiting at the ...

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Ultrasonic Extractor Pro-Lite
06/30/26

Pro-Lite™: Semi-Automated Ultrasonic Extractor for Pilot-Scale Production

Ultrasonic Extractor Pro-Lite

We are excited to spotlight theUltrasonic Extractor Pro-Lite™— a sem...

Read more...
What Is an Ultrasonic Processor? A Beginner’s Guide
06/26/26

What Is an Ultrasonic Processor? A Beginner’s Guide

What Is an Ultrasonic Processor? A Beginner’s Guide

An ultrasonic processor is a device that uses high-frequency sound w...

Read more...

 

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All-Natural CBD Extract Nanoemulsion
CASE STUDY

Download PDF

Ultrasonic Nanocrystallization
CASE STUDY

Download PDF

Ultrasonic Disruption of Yeast Cells
CASE STUDY

Download PDF

Scaling Up the Production of a Nanoemulsion
CASE STUDY

Download PDF

Read more case studies

Khara Cartagena, Cannabis and Hemp Productions

“We recently purchased a BSP-1200 system from ISM and were very impressed with its performance. The word got out, and one of our customers came to our facility to perform CBD-oil emulsion tests with the system. Though he was initially skeptical, after running the machine for only 1 min he got far better results to what he was able to achieve in over an hour with his conventional ultrasonic processor. He absolutely loved the BSP-1200 and bought it off from us that same day to take to his facility in CA! We have now decided to go straight for ISM’s production-scale ISP-3000 processor.”

See all testimonials

See all testimonials

EFFICIENT COOLING OF PIEZOELECTRIC TRANSDUCERS

United States Patent # 9,142,751, September 22, 2015

Alexey S. Peshkovsky, Sergei L. Peshkovsky

Abstract: A sealed piezoelectric transducer having a single, uniform, electrically insulating, heat-conducting layer of a soft, rubbery material filled with a fine, homogeneously-dispersed powder having high thermal conductivity. The material is placed in contact with the surfaces of the transducer and conducts the heat from the surfaces to an external heat sink. Since the thermally conductive powder is fully encapsulated in the rubbery material, its abrasive properties are neutralized.

See all intellectual property

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See all patents

High ultrasonic amplitudes able to generate intense acoustic cavitation are required for most processes.

Unlike conventional ultrasonic devices, our patented Barbell Horn Ultrasonic Technology (BHUT)-based processors make it possible to produce extremely high ultrasonic amplitudes at any scale, from laboratory to industrial, guaranteeing reproducible results after scale-up.

Learn More

 
Newest Advancements in ISM Ultrasonic Technology and Nano-Formulations
Ultrasonic Tools for Advanced Composite Manufacturing, by Dr. Alexey Peshkovsky at CAMX 2025
Water-Soluble Cannabinoids, Alkaloids & Other Bioactives: 2023 NECANN
Large-Capacity In-Line Filter: Assembly, Nanoemulsion Filtration, Cleaning, & Storage Procedures
Industrial Sonomechanics® at MJBizCon 2021 in Las Vegas, NV
“Water-Soluble” Cannabis: Ultrasonic Production of Liquid & Powdered Nanoemulsions
Barbell Horn Ultrasonic Technology (BHUT) Introduction and How We Scale Up
Interview with Dr. Alexey Peshkovsky at 2021 CBDExpo
Overview of Nano-Emulsification Process with BSP-1200 Ultrasonic Processor
Water-Soluble Cannabis Extract Nanoemulsions, by Dr. Alexey Peshkovsky, Industrial Sonomechanics
Dr. Alexey Peshkovsky speaking at the University of Cauca, Colombia
Podcast: Make & Measure the Potency of Cannabis Extract Nanoemulsions
Plant 2 Product: Production of Cannabis Beverages & Water-Soluble Powders
Barbell Horn Replacement Procedure for ISM Ultrasonic Processors
Do I Need Technical Background to Make Nanoemulsions with ISM Technology
 
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Frequently Asked Questions

What is an ultrasonic homogenizer used for?

An ultrasonic homogenizer uses high-frequency sound waves to generate intense cavitation in liquids — used for nanoemulsions, dispersing particles, plant extraction, degassing, and nano-crystallization across pharmaceutical, cannabis, cosmetic, and industrial applications.

What is the difference between a sonicator and a ultrasonic homogenizer?

The terms are often used interchangeably, as many understand both terms to describe a system that has a horn|probe|sonicator that emits ultrasonic energy in liquids thereby creating intense cavitiation and resulting nanoemulsions, dispersions and extraction.

Can ISM ultrasonic processors scale from lab to industrial production?

Yes. ISM’s patented Barbell Horn® Ultrasonic Technology (BHUT) maintains the same amplitudes and process outcomes when scaling from the LSP-600 lab unit to the ISP-3600 industrial processor — a key advantage over conventional sonicators.

What industries use ISM ultrasonic liquid processors?

ISM serves pharmaceutical, medical cannabis, nutraceutical, cosmetic & dermatological, food & beverage, paint & coatings, pesticide, and industrial fuel sectors.

How do I get started with ISM ultrasonic technology?

Schedule a consultation with an ISM application specialist, request a quotation, or explore the Knowledge Hub for SOPs, case studies, and videos.

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Webcast Recording: Ultrasonic Liquid Processing for Cannabis Oil Nano-Emulsification & Extraction