
- Produce mushroom, kava, and kratom extracts readily water-soluble.
- Eliminate the need for formulation and process development.
- Create all-natural, permanently stable nanoemulsions.
- Convert the nanoemulsions into water-soluble powders.
Overview

Manufacturers who would like to produce their own water-soluble liquid and powdered extracts of kratom, mushroom, kava, and other bioactive extracts that are poorly soluble in both water and oil — but do not have the capability or desire to develop their own formulations and processing procedures — can take advantage of ISM’s All-In-One NanoStabilizer®-LSSP. This formulation comprises natural, food-grade emulsifiers and stabilizers supplied in powder form. It is designed to work with our laboratory, bench, and industrial ultrasonic processors and includes step-by-step processing instructions. NanoStabilizer®-LSSP is tasteless and makes it possible to easily and quickly produce permanently stable, fully water-soluble nanoemulsions with median droplet sizes typically in the range of 60–250 nm (depending on the extract type and quality). Water-soluble powders obtained by drying these nanoemulsions readily reconstitute into the original liquid when mixed with water.
Science in a Jar
NanoStabilizer®-LSSP is an all-natural, all-in-one formulation that eliminates the need to develop emulsifier systems or processing procedures, as we have already done this work for you. It is an essential component of a cost-effective and complete solution designed specifically for bio-active extracts that are poorly soluble in both water and oil, such as those derived from mushrooms, kava, and kratom. NanoStabilizer®-LSSP offers the following distinct advantages:
- Water Compatibility: Enables the production of water-soluble liquids and powders, creating new opportunities for product innovation.
- Superior Stability: Maintains the physical stability of the bio-active extracts in water. No settling or floating — no shaking required.
- Direct Drying: Nanoemulsions based on NanoStabilizer®-LSSP can be dried directly (with nothing added) using multiple drying methods.
- Reconstitution Intelligence: Once added to water, powders created with NanoStabilizer®-LSSP reconstitute into the original nanoemulsions, allowing producers to maintain their intended product performance and bioavailability profiles.
- Natural Ingredients: Made with only natural ingredients. A specification sheet that includes the ingredient list is provided with purchase.
What is needed to produce water-soluble mushroom, kava, and kratom extracts?
Similar to our NanoStabilizer®-LSO formulation, NanoStabilizer®-LSSP makes it possible for both small-scale developers and industrial manufacturers to easily produce water-soluble bio-active liquids and powders that can be added to beverages and edibles or consumed directly as fast-dissolving tablets, using the following components and equipment:
- ISM high-intensity ultrasonic processor, high-pressure homogenizer, or similar
- NanoStabilizer®-LSSP
- Mushroom, kava, kratom, or another extract that is poorly soluble in both water and oil
- Distilled water
- Drying method/equipment
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Frequently Asked Questions
What is NanoStabilizer®-LSSP used for?
NanoStabilizer®-LSSP is ISM’s all-natural, all-in-one nano emulsifier specifically designed for bioactive extracts that are poorly soluble in both water and oil — such as mushroom extracts (beta-glucans, reishi, lion’s mane, chaga), kratom alkaloids (mitragynine), and kava kavalactones. It enables companies to produce permanently stable, water-soluble nanoemulsion liquids and powders with droplet sizes of 60–250 nm, without needing to develop their own formulations.
What is the difference between NanoStabilizer®-LSSP and NanoStabilizer®-LSO?
The key difference is solubility profile. NanoStabilizer®-LSO is formulated for lipophilic (oil-soluble) compounds — such as CBD, THC, vitamins, terpenes, and essential oils. NanoStabilizer®-LSSP is specifically engineered for semi-polar extracts that are poorly soluble in both water and oil — including mushroom, kava, and kratom extracts. Using the wrong formulation for your extract type will result in poor stability and emulsification.
What droplet sizes does NanoStabilizer®-LSSP produce?
NanoStabilizer®-LSSP produces nanoemulsions with median droplet sizes typically in the range of 60–250 nm, depending on the extract type and quality. These droplet sizes are within the nanoemulsion range, ensuring high water compatibility, physical stability, and enhanced bioavailability of the incorporated bioactives.
Can NanoStabilizer®-LSSP be used to make powders?
Yes. Nanoemulsions produced with NanoStabilizer®-LSSP can be dried directly — using spray drying, freeze drying, or other drying methods — without adding any additional ingredients. The resulting water-soluble powders reconstitute into the original liquid nanoemulsion upon contact with water, maintaining the intended bioavailability profile and product performance.
What equipment is needed to use NanoStabilizer®-LSSP?
You need an ISM high-intensity ultrasonic processor (LSP-600, BSP-1200, or ISP-3600) or comparable high-pressure homogenizer, plus NanoStabilizer®-LSSP in powder form, your mushroom/kava/kratom extract, distilled water, and drying equipment if producing powders. Step-by-step processing instructions are included with every purchase.
